2026-05-15T13:32:08Z https://ijidms.com/index.php/files/oai

oai:ojs2.ijidms.com:article/1 2025-02-25T09:54:06Z files:ART

oai:ojs.ijidms.com:article/3 2026-01-09T06:06:26Z files:ART

Advances in Dental Biomaterials: Bridging Dentistry and Medicine for Improved Patient Outcomes Soumik Chatterjee I. Niyas Ahamed Mansi Aggarwal Subham Mandal Suraj Mandal Dental biomaterials, biocompatibility, regenerative dentistry, nanotechnology, smart materials, personalized dentistry. The field of dental biomaterials has undergone significant advancements, bridging the gap between dentistry and medicine to enhance patient outcomes. Modern biomaterials, including bioactive ceramics, nanocomposites, and regenerative scaffolds, have revolutionized dental treatments by improving biocompatibility, durability, and functionality. Innovations in tissue engineering, such as stem cell applications and 3Dprinted biomaterials, have further enhanced periodontal regeneration and implant integration. Additionally, interdisciplinary research in biomaterials science has led to the development of smart materials with antibacterial properties, minimizing post-treatment complications. This paper explores the latest advancements in dental biomaterials, their medical implications, and their role in personalized dentistry. The integration of biocompatible and regenerative materials not only improves oral health but also contributes to systemic health, highlighting the convergence of dentistry and medicine. Future research directions and challenges in clinical translation are also discussed to provide insights into the evolving landscape of dental biomaterials. Sujata Publications 2025-03-17 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf https://ijidms.com/index.php/files/article/view/3 10.62896/ijidms.v1.i1.01 International Journal of Integrative Dental and Medical Sciences; IJIDMS: Volume 1, Issue 1, March-April 2025; 1-6 3049-4222 eng https://ijidms.com/index.php/files/article/view/3/16

oai:ojs.ijidms.com:article/4 2026-01-09T06:06:26Z files:ART

Integrative Pain Management: Dental and Medical Strategies in the Treatment of Temporomandibular Joint Disorder Kishorwara Ramamoorthy Mridali Mehta Satender Khatri Vinay S Temporomandibular Joint Disorder, Integrative Pain Management, Occlusal Therapy, Pharmacological Treatment, Regenerative Medicine, Multidisciplinary Approach. Temporomandibular Joint Disorder (TMD) is a complex condition affecting the jaw joint and surrounding muscles, leading to chronic pain and functional impairments. Traditional treatment approaches have largely focused on either dental or medical interventions, often leading to limited success in long-term pain management. This paper explores an integrative pain management model that combines dental and medical strategies to improve patient outcomes. Key approaches include occlusal therapy, orthodontic interventions, physical therapy, pharmacological management, minimally invasive procedures, and behavioral therapies. The role of patient-centered care, multidisciplinary collaboration, and the incorporation of emerging techniques such as regenerative medicine and neuromodulation are also discussed. By addressing the multifactorial nature of TMD through a holistic and evidence-based approach, integrative pain management provides a promising avenue for enhancing treatment efficacy and improving patients' quality of life. Sujata Publications 2025-03-17 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf https://ijidms.com/index.php/files/article/view/4 10.62896/ International Journal of Integrative Dental and Medical Sciences; IJIDMS: Volume 1, Issue 1, March-April 2025; 7-14 3049-4222 eng https://ijidms.com/index.php/files/article/view/4/11

oai:ojs.ijidms.com:article/5 2026-01-09T06:06:26Z files:ART

Interdisciplinary Approaches to Managing Oral Cancer: Combining Dentistry, Oncology, and Surgery Madhumitha Ponmari K Aakash Kumar Jaiswal K. Arun Chand Roby Oral Cancer, Interdisciplinary Approach, Dentistry, Oncology, Surgery, Multidisciplinary Treatment, Patient-Centered Care Oral cancer presents a significant global health challenge, necessitating a multidisciplinary approach for effective management. This paper explores the integration of dentistry, oncology, and surgery in the diagnosis, treatment, and post-treatment rehabilitation of oral cancer patients. Early detection by dental professionals plays a crucial role in improving prognosis, while oncologists contribute to targeted therapies such as chemotherapy, immunotherapy, and radiation therapy. Surgical interventions, including tumor resection and reconstructive procedures, restore functionality and aesthetics. The collaboration among these disciplines enhances patient outcomes by ensuring comprehensive care, minimizing recurrence rates, and improving the quality of life. Challenges such as treatment delays, accessibility to specialized care, and the need for personalized treatment strategies are also discussed. The study highlights the importance of a holistic, patient-centered approach that integrates advancements in medical research, technology, and clinical expertise to optimize oral cancer management. Sujata Publications 2025-03-17 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf https://ijidms.com/index.php/files/article/view/5 10.62896/ International Journal of Integrative Dental and Medical Sciences; IJIDMS: Volume 1, Issue 1, March-April 2025; 15-21 3049-4222 eng https://ijidms.com/index.php/files/article/view/5/12

oai:ojs.ijidms.com:article/6 2026-01-09T06:06:26Z files:ART

Psychological Well-Being and Oral Health: The Role of Dentistry in Comprehensive Healthcare Monisha R Kartik Yadav Subham Mandal Suraj Mandal Oral Health, Psychological Well-being, Dentistry, Mental Health, Comprehensive Healthcare, Aesthetic Dentistry, Interdisciplinary Approach Oral health plays a crucial role in overall well-being, influencing both physical and psychological health. Poor oral hygiene and dental diseases are not only linked to systemic health conditions but also significantly impact an individual's self-esteem, social interactions, and mental health. This paper explores the intricate relationship between psychological well-being and oral health, emphasizing the role of dentistry in comprehensive healthcare. The study highlights how dental conditions such as tooth loss, malocclusion, and periodontal diseases contribute to stress, anxiety, and depression. Furthermore, it examines the psychological effects of dental treatments and aesthetic dentistry in restoring confidence and improving quality of life. Through a review of current literature and clinical studies, this research underscores the need for an integrated healthcare approach where dentistry collaborates with mental health professionals to provide holistic patient care. By addressing both the physical and psychological aspects of oral health, dentistry can play a transformative role in enhancing overall health outcomes. The study concludes with recommendations for interdisciplinary strategies to bridge the gap between oral health and mental well-being, advocating for policies that promote awareness, accessibility, and mental health support in dental care settings. Sujata Publications 2025-03-17 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf https://ijidms.com/index.php/files/article/view/6 10.62896/ International Journal of Integrative Dental and Medical Sciences; IJIDMS: Volume 1, Issue 1, March-April 2025; 22-29 3049-4222 eng https://ijidms.com/index.php/files/article/view/6/13

oai:ojs.ijidms.com:article/7 2026-01-09T06:06:26Z files:ART

The Role of Oral Microbiota in Systemic Diseases: Bridging the gap between Dentistry and Medicine Atika Ismail Pavan Kumar K R Suraj Mandal Oral microbiota, Systemic diseases, Dysbiosis, Periodontal disease, Inflammation, Cardiovascular disease, Diabetes, Respiratory infections Oral microbiota, a diverse community of microorganisms residing in the oral cavity, plays a crucial role in maintaining oral and systemic health. Recent research highlights the intricate link between oral microbiota and various systemic diseases, including cardiovascular disease, diabetes, respiratory infections, rheumatoid arthritis, and neurological disorders. Dysbiosis, an imbalance in microbial composition, can lead to periodontal disease, which acts as a reservoir of inflammation and pathogenic bacteria, exacerbating systemic conditions. The bidirectional relationship between oral health and systemic diseases underscores the need for interdisciplinary collaboration between dentistry and medicine. This paper explores the mechanisms through which oral microbiota influences systemic health, examines key microbial pathogens involved in disease progression, and discusses emerging diagnostic and therapeutic strategies aimed at leveraging oral microbiota for disease prevention and treatment. Bridging the gap between dentistry and medicine through a holistic approach to patient care can enhance early detection, personalized treatment, and overall health outcomes. Sujata Publications 2025-03-17 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf https://ijidms.com/index.php/files/article/view/7 10.62896/ International Journal of Integrative Dental and Medical Sciences; IJIDMS: Volume 1, Issue 1, March-April 2025; 30-36 3049-4222 eng https://ijidms.com/index.php/files/article/view/7/14

oai:ojs.ijidms.com:article/10 2026-01-09T06:06:00Z files:ART

Advances in Preventive Dentistry: Clinical Strategies for Long-Term Oral Health Swesha Chhabra Preventive dentistry; Oral health promotion; Dental caries prevention; Periodontal disease; Fluoride therapy; Risk assessment; Minimally invasive dentistry Preventive dentistry has emerged as a cornerstone of modern oral healthcare, focusing on the prevention of oral diseases rather than their treatment at advanced stages. With increasing awareness of the link between oral health and systemic well-being, preventive strategies have evolved to incorporate evidence-based clinical practices, patientcentered care, and innovative technologies. This manuscript explores recent advances in preventive dentistry, highlighting contemporary clinical strategies aimed at achieving long-term oral health. Key areas discussed include risk assessment, oral hygiene practices, fluoride therapy, dietary counseling, minimally invasive dentistry, behavioral interventions, and the integration of digital tools in preventive care. Emphasis is placed on individualized prevention plans, early disease detection, and interdisciplinary collaboration. By adopting comprehensive preventive approaches, dental professionals can significantly reduce the burden of oral diseases, enhance patient quality of life, and promote sustainable oral healthcare outcomes. Sujata Publications 2025-05-21 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf https://ijidms.com/index.php/files/article/view/10 10.62896/ International Journal of Integrative Dental and Medical Sciences; IJIDMS: Volume 1, Issue 2, May-June 2025; 1-5 3049-4222 eng https://ijidms.com/index.php/files/article/view/10/17

oai:ojs.ijidms.com:article/11 2026-01-09T06:06:00Z files:ART

Dental Caries and Periodontal Diseases: An Integrative Clinical Perspective Greeshma K Dental caries; Periodontal disease; Oral health; Integrative dentistry; Plaque biofilm; Preventive care; Clinical management Dental caries and periodontal diseases are the two most prevalent oral health conditions affecting populations worldwide and remain leading causes of tooth loss and compromised quality of life. Traditionally viewed as distinct pathological entities, growing clinical and biological evidence highlights significant interrelationships between these diseases. This manuscript presents an integrative clinical perspective on dental caries and periodontal diseases, emphasizing shared etiological factors, overlapping risk determinants, and coordinated preventive and therapeutic strategies. The paper discusses the microbial, behavioral, systemic, and environmental influences contributing to disease progression, along with modern diagnostic approaches and patientcentered management. By integrating preventive dentistry, periodontal therapy, restorative care, and behavioral interventions, clinicians can improve long-term oral and systemic health outcomes. This holistic approach supports comprehensive oral healthcare that aligns with contemporary clinical practice and public health goals. Sujata Publications 2025-05-21 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf https://ijidms.com/index.php/files/article/view/11 10.62896/ International Journal of Integrative Dental and Medical Sciences; IJIDMS: Volume 1, Issue 2, May-June 2025; 6-10 3049-4222 eng https://ijidms.com/index.php/files/article/view/11/18

oai:ojs.ijidms.com:article/12 2026-01-09T06:06:00Z files:ART

Impact of Oral Hygiene Practices on Systemic Health Outcomes Mohit MP Oral hygiene; Systemic health; Periodontal disease; Inflammation; Oral-systemic link; Preventive care; Integrated healthcare Oral hygiene practices are fundamental to maintaining oral health, yet growing evidence suggests their influence extends far beyond the oral cavity. Poor oral hygiene contributes to the development of periodontal diseases and chronic oral infections, which may serve as sources of systemic inflammation and microbial dissemination. This manuscript examines the impact of oral hygiene practices on systemic health outcomes, emphasizing biological mechanisms, clinical associations, and preventive strategies. It explores the role of oral biofilm control in reducing systemic disease risk, highlights connections between oral health and cardiovascular diseases, diabetes, respiratory conditions, adverse pregnancy outcomes, and overall immune function. The paper underscores the importance of integrated dental–medical care and patient education in promoting holistic health and improving long-term health outcomes. Sujata Publications 2025-05-21 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf https://ijidms.com/index.php/files/article/view/12 10.62896/ International Journal of Integrative Dental and Medical Sciences; IJIDMS: Volume 1, Issue 2, May-June 2025; 11-15 3049-4222 eng https://ijidms.com/index.php/files/article/view/12/19

oai:ojs.ijidms.com:article/13 2026-01-09T06:06:00Z files:ART

Innovations in Restorative Dentistry: Materials, Techniques, and Clinical Outcomes Abhijeet Humne Restorative dentistry; Dental materials; Composite resins; Dental ceramics; Adhesive systems; Digital dentistry; Clinical outcomes Restorative dentistry has undergone significant transformation with the introduction of advanced materials, innovative techniques, and digital technologies aimed at improving clinical outcomes and patient satisfaction. Modern restorative approaches emphasize minimally invasive procedures, esthetics, durability, and biological compatibility while preserving natural tooth structure. This manuscript explores recent innovations in restorative dentistry, focusing on contemporary restorative materials, evolving clinical techniques, and their impact on functional and esthetic outcomes. It discusses advances in composite resins, ceramics, bioactive materials, adhesive systems, and digital workflows, along with their clinical applications. Emphasis is placed on evidenceinformed decision-making, patient-centered care, and long-term restoration success. These innovations collectively contribute to enhanced oral health, improved quality of life, and sustainable restorative dental practices. Sujata Publications 2025-05-21 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf https://ijidms.com/index.php/files/article/view/13 10.62896/ International Journal of Integrative Dental and Medical Sciences; IJIDMS: Volume 1, Issue 2, May-June 2025; 16-20 3049-4222 eng https://ijidms.com/index.php/files/article/view/13/20

oai:ojs.ijidms.com:article/14 2026-01-09T06:06:00Z files:ART

Oral Health Awareness and Its Role in Public Health Promotion Pavan Kumar Koralakunte Ravi Oral health awareness; Public health promotion; Preventive dentistry; Health education; Community health; Oral-systemic health; Health behavior Oral health is an essential component of overall health and well-being, yet it is often neglected in public health planning and individual health practices. Oral diseases such as dental caries, periodontal diseases, and oral infections remain highly prevalent and largely preventable. Oral health awareness plays a critical role in reducing the burden of these conditions and promoting healthier communities. This manuscript explores the significance of oral health awareness in public health promotion, highlighting its impact on disease prevention, health behavior modification, and quality of life. It discusses the relationship between oral health and systemic health, the importance of education and community engagement, and the role of healthcare professionals and policymakers in advancing oral health awareness. Strengthening oral health awareness through integrated public health strategies can contribute to improved health outcomes and reduced healthcare disparities. Sujata Publications 2025-05-21 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf https://ijidms.com/index.php/files/article/view/14 10.62896/ International Journal of Integrative Dental and Medical Sciences; IJIDMS: Volume 1, Issue 2, May-June 2025; 21-25 3049-4222 eng https://ijidms.com/index.php/files/article/view/14/21

oai:ojs.ijidms.com:article/15 2026-01-09T06:29:14Z files:ART

Clinical Outcomes of Oral and Maxillofacial Surgical Interventions: A Retrospective Study Kohinoor Acharya Oral and maxillofacial surgery; Clinical outcomes; Retrospective study; Surgical interventions; Postoperative complications; Patient recovery Oral and maxillofacial surgery plays a critical role in the diagnosis and management of a wide range of conditions affecting the oral cavity, jaws, face, and associated structures. Evaluating clinical outcomes of surgical interventions is essential for improving patient care, surgical planning, and long-term prognosis. This retrospective study analyzes the clinical outcomes of various oral and maxillofacial surgical procedures performed over a defined period, focusing on treatment success, postoperative complications, and patient recovery. The findings highlight the effectiveness of contemporary surgical techniques, the influence of patient-related factors, and the importance of comprehensive preoperative assessment and postoperative care. The study underscores the value of outcome-based evaluation in enhancing surgical quality and optimizing patient-centered care in oral and maxillofacial surgery. Sujata Publications 2026-01-09 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf https://ijidms.com/index.php/files/article/view/15 10.62896/ International Journal of Integrative Dental and Medical Sciences; IJIDMS: Volume 1, Issue 3, July-August 2025; 1-3 3049-4222 eng https://ijidms.com/index.php/files/article/view/15/22

oai:ojs.ijidms.com:article/16 2026-01-09T06:29:14Z files:ART

Advances in Maxillofacial Trauma Management and Rehabilitation Dishant Kumar Sonpal Maxillofacial trauma; Facial fractures; Trauma management; Surgical fixation; Rehabilitation; Functional recovery; Oral and maxillofacial surgery Maxillofacial trauma represents a significant clinical challenge due to its complex anatomical involvement, functional implications, and psychosocial impact on patients. Injuries to the facial skeleton and associated soft tissues often result from road traffic accidents, interpersonal violence, falls, and sports-related incidents. Advances in maxillofacial trauma management have led to improved diagnostic accuracy, surgical precision, and rehabilitation outcomes. This manuscript provides a comprehensive overview of contemporary advances in the assessment, management, and rehabilitation of maxillofacial trauma. Emphasis is placed on modern imaging techniques, surgical approaches, fixation systems, multidisciplinary care, and rehabilitative strategies aimed at restoring function, esthetics, and quality of life. The integration of innovative technologies and patient-centered rehabilitation protocols has significantly enhanced clinical outcomes and long-term recovery in maxillofacial trauma patients. Sujata Publications 2025-08-28 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf https://ijidms.com/index.php/files/article/view/16 10.62896/ International Journal of Integrative Dental and Medical Sciences; IJIDMS: Volume 1, Issue 3, July-August 2025; 4-8 3049-4222 eng https://ijidms.com/index.php/files/article/view/16/23

oai:ojs.ijidms.com:article/17 2026-01-09T06:29:14Z files:ART

Minimally Invasive Techniques in Oral and Maxillofacial Surgery Kiran Srinivas B Minimally invasive surgery; Oral and maxillofacial surgery; Endoscopic techniques; Digital planning; Patient-centered care; Surgical innovation Minimally invasive techniques have transformed the field of oral and maxillofacial surgery by reducing surgical trauma, enhancing precision, and improving patient-centered outcomes. These approaches aim to achieve optimal therapeutic results while minimizing tissue damage, postoperative pain, complications, and recovery time. Advances in imaging, instrumentation, endoscopic assistance, and digital planning have expanded the scope of minimally invasive procedures in the management of dentoalveolar conditions, maxillofacial trauma, temporomandibular joint disorders, and reconstructive surgery. This manuscript provides a comprehensive overview of minimally invasive techniques in oral and maxillofacial surgery, highlighting their principles, clinical applications, benefits, limitations, and future directions. The integration of these techniques into routine practice represents a significant step toward safer, more efficient, and patientfriendly surgical care. Sujata Publications 2026-01-09 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf https://ijidms.com/index.php/files/article/view/17 10.62896/ International Journal of Integrative Dental and Medical Sciences; IJIDMS: Volume 1, Issue 3, July-August 2025; 9-13 3049-4222 eng https://ijidms.com/index.php/files/article/view/17/24

oai:ojs.ijidms.com:article/18 2026-01-09T06:29:14Z files:ART

Dietary Polyphenols and their Protective Role Against Carcinogenesis Jayesh Baldota Polyphenols, carcinogenesis, cancer prevention, antioxidants, bioavailability, inflammation, cell signaling, gene expression, dietary factors. Dietary polyphenols, a diverse group of bioactive compounds found in fruits, vegetables, grains, and beverages like tea and wine, have gained considerable attention for their potential to prevent cancer. This paper explores the protective role of polyphenols against carcinogenesis, examining their mechanisms of action, including antioxidant activity, modulation of cell signaling pathways, regulation of gene expression, and inhibition of inflammation. Through a review of experimental studies and clinical trials, the research highlights how polyphenols can interfere with various stages of cancer development, such as initiation, promotion, and progression. The paper further discusses the bioavailability and metabolism of polyphenols, which may influence their efficacy in cancer prevention. Despite challenges in translating preclinical findings into clinical practice, the existing evidence supports the notion that a polyphenol-rich diet may reduce the risk of certain types of cancer. Sujata Publications 2026-01-09 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf https://ijidms.com/index.php/files/article/view/18 10.62896/ International Journal of Integrative Dental and Medical Sciences; IJIDMS: Volume 1, Issue 3, July-August 2025; 14-20 3049-4222 eng https://ijidms.com/index.php/files/article/view/18/25

oai:ojs.ijidms.com:article/19 2026-01-09T06:29:14Z files:ART

Obesity-Linked Metabolic Alterations as Drivers of Carcinogenesis Arindam Kolay obesity, carcinogenesis, metabolic alterations, adipose tissue, insulin resistance, inflammation, adipokines, tumor microenvironment, immune evasion, angiogenesis, cancer prevention. Obesity has become a global health epidemic, and growing evidence suggests that it plays a significant role in the development and progression of various types of cancer. This paper explores the metabolic alterations associated with obesity that contribute to carcinogenesis, focusing on changes in adipose tissue, insulin resistance, inflammatory pathways, and altered hormone regulation. The accumulation of excess fat, particularly visceral fat, leads to chronic low-grade inflammation, dysregulated adipokine secretion, and enhanced growth factor signaling, all of which can promote tumor initiation and progression. Additionally, the paper discusses the impact of obesity on the tumor microenvironment, immune evasion, and angiogenesis. Understanding these obesity-linked metabolic alterations provides valuable insights into potential therapeutic strategies for preventing or treating cancer in obese individuals. The aim of this research is to underline the importance of addressing obesity as a modifiable risk factor in cancer prevention and to highlight the complex interplay between metabolic dysfunction and cancer biology Sujata Publications 2026-01-09 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf https://ijidms.com/index.php/files/article/view/19 10.62896/ International Journal of Integrative Dental and Medical Sciences; IJIDMS: Volume 1, Issue 3, July-August 2025; 27-33 3049-4222 eng https://ijidms.com/index.php/files/article/view/19/26

oai:ojs.ijidms.com:article/20 2026-01-09T07:38:14Z files:ART

Epigenetic Alterations in Carcinogenesis: Role of DNA Methylation and Histone Modifications Shivanand Kolageri Epigenetics, Carcinogenesis, DNA Methylation, Histone Modifications, Gene Expression, Tumor Suppressor Genes, Oncogenes, Chromatin, Cancer Therapy Epigenetic alterations, particularly DNA methylation and histone modifications, play a crucial role in the initiation, progression, and metastasis of cancer. Unlike genetic mutations, which involve changes in the DNA sequence, epigenetic modifications are reversible and can be influenced by environmental factors, lifestyle, and age. DNA methylation, the addition of a methyl group to the 5’ position of cytosine residues, typically leads to gene silencing and has been associated with the inactivation of tumor suppressor genes. On the other hand, histone modifications, including acetylation, methylation, and phosphorylation, influence chromatin structure and gene expression. These modifications can either promote or inhibit the expression of oncogenes and tumor suppressor genes, depending on the specific modification and context. This paper reviews the roles of DNA methylation and histone modifications in carcinogenesis, exploring their impact on gene expression regulation, tumor progression, and potential for therapeutic intervention. A comprehensive understanding of these epigenetic mechanisms may open new avenues for early detection, targeted therapy, and the development of epigenetic drugs in cancer treatment. Sujata Publications 2026-01-09 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf https://ijidms.com/index.php/files/article/view/20 10.62896/ International Journal of Integrative Dental and Medical Sciences; IJIDMS: Volume 1, Issue 4, September-October 2025; 1-7 3049-4222 eng https://ijidms.com/index.php/files/article/view/20/27

oai:ojs.ijidms.com:article/21 2026-01-09T07:38:14Z files:ART

Oncogenic Signaling Pathways in Tumor Progression: An Update on PI3K/AKT/MTOR and MAPK axis Savita Sambhaji Patil Oncogenic signaling, PI3K/AKT/mTOR pathway, MAPK pathway, tumor progression, cancer therapy, molecular mechanisms, targeted therapies, cellular proliferation, metastasis, kinase inhibitors. Oncogenic signaling pathways play a crucial role in the initiation, progression, and metastasis of various cancers. Among these, the PI3K/AKT/mTOR and MAPK signaling axes are frequently implicated in tumorigenesis and are considered key drivers of tumor cell survival, proliferation, and resistance to therapy. The PI3K/AKT/mTOR pathway regulates cellular processes such as growth, metabolism, and survival, while the MAPK pathway, comprising multiple kinases like ERK, JNK, and p38, is involved in cell differentiation, migration, and stress responses. Dysregulation of these pathways often results in uncontrolled cellular proliferation and metastasis. Recent advances in understanding the molecular mechanisms underlying these signaling pathways have led to the development of targeted therapies aimed at inhibiting specific components within these pathways. This paper provides a comprehensive update on the role of the PI3K/AKT/mTOR and MAPK axes in tumor progression, focusing on their molecular interactions, functional implications in cancer, and the emerging therapeutic strategies targeting these pathways. Understanding these signaling networks is critical for developing more effective treatments for cancer patients. Sujata Publications 2026-01-09 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf https://ijidms.com/index.php/files/article/view/21 10.62896/ International Journal of Integrative Dental and Medical Sciences; IJIDMS: Volume 1, Issue 4, September-October 2025; 8-15 3049-4222 eng https://ijidms.com/index.php/files/article/view/21/28

oai:ojs.ijidms.com:article/22 2026-01-09T07:38:14Z files:ART

Molecular Crosstalk Between Chronic Inflammation and Cancer Development Sravani Boyapati Chronic inflammation, cancer development, molecular crosstalk, tumor initiation, tumor progression, signaling pathways, NFκB, JAK-STAT, MAPK, cytokines, chemokines, growth factors, reactive oxygen species, DNA damage, genomic instability, immune evasion, tumor microenvironment Chronic inflammation is increasingly recognized as a critical driver of cancer development, contributing to tumor initiation, progression, and metastasis. The molecular crosstalk between chronic inflammation and cancer involves complex signaling networks that alter cellular behavior and the tumor microenvironment. Inflammatory mediators, such as cytokines, chemokines, and growth factors, activate signaling pathways like NF-κB, JAK-STAT, and MAPK, which promote cell proliferation, survival, angiogenesis, and immune evasion. Additionally, chronic inflammation leads to the accumulation of reactive oxygen and nitrogen species, which induce DNA damage, further driving genomic instability. This paper explores the molecular mechanisms underlying the inflammatory response in cancer, focusing on the bidirectional interaction between immune cells and cancer cells. By examining key signaling molecules, transcription factors, and immune modulators involved in this crosstalk, the paper highlights potential therapeutic targets aimed at disrupting the inflammatory pathways that fuel carcinogenesis. Understanding the intricate relationship between chronic inflammation and cancer is crucial for the development of novel preventive and therapeutic strategies to combat inflammation-driven cancers. Sujata Publications 2026-01-09 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf https://ijidms.com/index.php/files/article/view/22 10.62896/ International Journal of Integrative Dental and Medical Sciences; IJIDMS: Volume 1, Issue 4, September-October 2025; 16-23 3049-4222 eng https://ijidms.com/index.php/files/article/view/22/29

oai:ojs.ijidms.com:article/23 2026-01-09T07:38:14Z files:ART

The Emerging Role of Non-Coding RNAs in Carcinogenesis and Tumor Metastasis Nripendra Singh Non-coding RNAs, carcinogenesis, tumor metastasis, microRNAs, long non-coding RNAs, circular RNAs, cancer progression, biomarkers, gene regulation, therapeutic targets. Non-coding RNAs (ncRNAs) have emerged as crucial regulators of cellular processes, including gene expression, chromatin remodeling, and cellular signaling. Recent advancements in molecular biology have uncovered their pivotal role in carcinogenesis and tumor metastasis. These ncRNAs, including microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs), regulate a variety of biological pathways that govern tumor initiation, progression, and spread to distant organs. miRNAs are involved in post-transcriptional regulation and can act as either tumor suppressors or oncogenes, depending on the target genes they regulate. lncRNAs contribute to the formation of complex molecular networks that modulate tumor cell proliferation, apoptosis, and migration. Furthermore, circRNAs, with their unique stable structure, are being recognized as key regulators of metastasisrelated pathways. The dysregulation of these ncRNAs in cancerous cells highlights their potential as biomarkers for early diagnosis and therapeutic targets. Understanding the role of ncRNAs in carcinogenesis and metastasis is crucial for the development of novel diagnostic and therapeutic strategies, offering hope for more effective cancer treatments in the future. Sujata Publications 2026-01-09 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf https://ijidms.com/index.php/files/article/view/23 10.62896/ International Journal of Integrative Dental and Medical Sciences; IJIDMS: Volume 1, Issue 4, September-October 2025; 24-31 3049-4222 eng https://ijidms.com/index.php/files/article/view/23/30

oai:ojs.ijidms.com:article/24 2026-01-09T07:38:14Z files:ART

Oxidative Stress and Reactive Oxygen Species in Tumor Initiation and Progression Ruchismita Manna Oxidative stress, Reactive oxygen species, Tumor initiation, Tumor progression, Cancer, DNA damage, Genomic instability, Oncogenes, Angiogenesis, Metastasis, Antioxidants, Cancer therapy, Tumor microenvironment Oxidative stress and reactive oxygen species (ROS) have gained significant attention as key players in the initiation and progression of various cancers. The imbalance between ROS production and the body's antioxidant defenses creates a cellular environment conducive to genetic mutations, inflammation, and alterations in cellular signaling pathways. This paper explores the role of oxidative stress and ROS in tumorigenesis, examining how they contribute to DNA damage, genomic instability, and the activation of oncogenes. Moreover, we discuss the complex relationship between ROS and tumor progression, emphasizing their influence on angiogenesis, metastasis, and resistance to therapy. Furthermore, the potential of antioxidant strategies and ROS-targeting therapies for cancer prevention and treatment are explored. This review highlights the necessity of understanding the molecular mechanisms through which oxidative stress and ROS influence cancer development, with the goal of identifying novel therapeutic targets and improving clinical outcomes. Sujata Publications 2026-01-09 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf https://ijidms.com/index.php/files/article/view/24 10.62896/ International Journal of Integrative Dental and Medical Sciences; IJIDMS: Volume 1, Issue 4, September-October 2025; 32-38 3049-4222 eng https://ijidms.com/index.php/files/article/view/24/31

oai:ojs.ijidms.com:article/25 2026-01-09T08:47:09Z files:ART

Transforming Oral Healthcare Through AI: A White Paper on SwaLife Oral Disease Diagnosis Pravin Badhe Artificial intelligence; Oral healthcare; Dental diagnostics; Oral disease detection; Machine learning; Precision dentistry; SwaLife Artificial intelligence (AI) is rapidly transforming healthcare by enabling early detection, accurate diagnosis, and personalized treatment planning. In dentistry, AI-driven technologies are emerging as powerful tools forimproving the diagnosis and management of oral diseases. This white paper presents SwaLife Oral Disease Diagnosis, an AI-enabled platform designed to enhance oral healthcare through intelligent analysis of clinical data, dental images, and patient-specific information. By integrating machine learning algorithms with dental expertise, the system supports early identification of oral pathologies, risk assessment, and decision support for clinicians. The application of AI in oral disease diagnosis has the potential to improve diagnostic accuracy, reduce variability, optimize clinical workflows, and promote preventive care. This white paper highlights the role of AI-powered solutions in advancing precision dentistry and shaping the future of oral healthcare delivery. Sujata Publications 2026-01-09 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf https://ijidms.com/index.php/files/article/view/25 10.62896/ International Journal of Integrative Dental and Medical Sciences; IJIDMS: Volume 1, Issue 5, November-December 2025; 1-6 3049-4222 eng https://ijidms.com/index.php/files/article/view/25/32

oai:ojs.ijidms.com:article/27 2026-01-09T08:47:09Z files:ART

Comparative Evaluation of Analgesic, Anti-Inflammatory, and Antipyretic Activities of Morus alba and Pyrus pyrifolia Suraj Mandal Herbal Medicine, Morus alba, Pyrus pyrifolia, Analgesic Properties, Anti-inflammatory Effects Herbal remedies have historically served as a fundamental aspect of conventional healing methods across the globe, with Morus alba (Mulberry) and Pyrus pyrifolia (Asian Pear) standing out as significant botanicals in Eastern medicinal practices. The objective of this research is to evaluate and contrast their medicinal characteristics, with particular emphasis on their pain-relieving, inflammation-reducing, and feverreducing effects. Morus alba boasts a wealth of flavonoids, anthocyanins, and resveratrol, whereas Pyrus pyrifolia is abundant in phenolic compounds, flavonoids, and tannins, all recognised for their beneficial antioxidant and anti-inflammatory effects. Both botanical specimens exhibit encouraging capabilities in mitigating discomfort and swelling, with Morus alba showcasing superior effectiveness in a range of assessments, such as the tail-flick test, formalin-induced pain evaluation, carrageenan-induced paw oedema analysis, and Brewer’s yeast-induced fever experiments. Moreover, both species demonstrate a slight level of toxicity, indicating a potentially advantageous safety profile for medicinal applications. The results indicate the promising capabilities of Morus alba and Pyrus pyrifolia as natural options for alleviating pain, reducing inflammation, and lowering fever, thereby encouraging additional clinical investigations to uncover their complete therapeutic benefits. Sujata Publications 2026-01-09 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf https://ijidms.com/index.php/files/article/view/27 10.62896/ International Journal of Integrative Dental and Medical Sciences; IJIDMS: Volume 1, Issue 5, November-December 2025; 7-17 3049-4222 eng https://ijidms.com/index.php/files/article/view/27/33

oai:ojs.ijidms.com:article/28 2026-01-09T08:47:09Z files:ART

Phytochemicals in Traditional Medicine: A Modern Approach to Evidence-Based Herbal Therapies Subham Mandal Suraj Mandal Phytochemicals, Traditional Medicine, Herbal Therapies, Evidence-Based Medicine, Pharmacology, Clinical Validation Phytochemicals, bioactive compounds found in plants, have been integral to traditional medicine systems worldwide, including Ayurveda, Traditional Chinese Medicine (TCM), and Indigenous healing practices. With the rise of modern scientific methodologies, there is an increasing emphasis on validating the therapeutic potential of these plant-derived compounds through evidence-based approaches. This paper explores the role of phytochemicals in traditional medicine, highlighting their pharmacological properties, mechanisms of action, and clinical applications. A comparative analysis of conventional herbal therapies and their integration into modern medicine is presented, emphasizing advancements in analytical techniques, clinical trials, and regulatory frameworks. The study also addresses challenges such as standardization, bioavailability, and potential toxicity, underscoring the need for rigorous scientific validation. By bridging the gap between traditional knowledge and modern research, this paper aims to promote the safe and effective use of phytochemicals in contemporary healthcare. Sujata Publications 2026-01-09 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf https://ijidms.com/index.php/files/article/view/28 10.62896/ International Journal of Integrative Dental and Medical Sciences; IJIDMS: Volume 1, Issue 5, November-December 2025; 18-27 3049-4222 eng https://ijidms.com/index.php/files/article/view/28/34

oai:ojs.ijidms.com:article/29 2026-01-09T08:47:09Z files:ART

Phytochemicals in Traditional Medicine: A Modern Approach to Evidence-Based Herbal Therapies Subham Mandal Suraj Mandal Purnima Singh Monkeypox, MPXV, antivirals, vaccines, immunomodulation, CRISPR, nanomedicine, public health. Monkeypox (Mpox), a zoonotic disease caused by the Monkeypox virus (MPXV), has reemerged as a significant global public health challenge. Historically endemic to Central and West Africa, its spread to non-endemic regions during the 2022 outbreak underscored the need for innovative therapeutic and preventive strategies. Traditional Mpox management has relied on repurposed smallpox antivirals and vaccines, such as Tecovirimat and Jynneos, but challenges persist in terms of drug resistance, accessibility, affordability, and vaccine hesitancy. Recent advancements include the development of nextgeneration antivirals, monoclonal antibodies, immunomodulatory therapies, and host-targeted treatments. Emerging technologies like CRISPR gene editing, nanomedicine, and artificial intelligence-driven drug discovery are poised to revolutionize Mpox treatment, offering precision-targeted interventions and enhanced outcomes. Furthermore, public health strategies inspired by smallpox eradication highlight the importance of equitable vaccine distribution, robust surveillance, and international collaboration. Addressing current challenges while leveraging these advancements holds promise for reducing Mpox's burden and preventing future outbreaks. Achieving global eradication will require sustained investment in innovative science, healthcare infrastructure, and global health policies. Sujata Publications 2026-01-09 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf https://ijidms.com/index.php/files/article/view/29 10.62896/ International Journal of Integrative Dental and Medical Sciences; IJIDMS: Volume 1, Issue 5, November-December 2025; 28-39 3049-4222 eng https://ijidms.com/index.php/files/article/view/29/35

oai:ojs.ijidms.com:article/30 2026-01-09T08:47:09Z files:ART

Orthodontic Treatment and Its Impact on Oral Health–Related Quality of Life Kohinoor Acharya Orthodontic treatment; Oral health–related quality of life; Malocclusion; Patient satisfaction; Psychosocial impact; Dental esthetics Orthodontic treatment plays a significant role in improving dental alignment, occlusion, facial esthetics, and overall oral function. Beyond clinical outcomes, orthodontic care has a substantial influence on oral health–related quality of life (OHRQoL), which encompasses physical, psychological, and social well-being. Malocclusion can negatively affect mastication, speech, self-esteem, and social interactions, thereby impacting daily life. This manuscript explores the relationship between orthodontic treatment and OHRQoL, highlighting changes experienced by patients before, during, and after treatment. Emphasis is placed on functional improvement, psychosocial benefits, treatment-related discomfort, and long-term patient satisfaction. Understanding the multidimensional effects of orthodontic therapy is essential for patientcentered care, informed consent, and outcome assessment in contemporary orthodontic practice. Sujata Publications 2026-01-09 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf https://ijidms.com/index.php/files/article/view/30 10.62896/ International Journal of Integrative Dental and Medical Sciences; IJIDMS: Volume 1, Issue 5, November-December 2025; 40-45 3049-4222 eng https://ijidms.com/index.php/files/article/view/30/36

oai:ojs.ijidms.com:article/31 2026-02-14T08:00:14Z files:ART

MRI Evaluation of Different Types of Cerebral Metastases Dr. Sangam Gupta Younus Syed Uz Zaman Y. P. Sachdev Cerebral metastases; Magnetic Resonance Imaging; Brain metastasis; Contrast enhancement; Diffusion-weighted imaging; MR spectroscopy Background: Cerebral metastases represent the most common intracranial tumors in adults and are associated with significant morbidity and mortality. Magnetic Resonance Imaging (MRI) is the imaging modality of choice for detection, characterization, and evaluation of brain metastases due to its superior soft-tissue contrast and multiparametric capabilities. Aim: To evaluate the MRI characteristics of different types of cerebral metastases and correlate their imaging features with the primary tumor origin. Materials and Methods: This retrospective descriptive case series included six patients with histopathologically or PET-CT–confirmed primary malignancies and radiologically diagnosed cerebral metastases. All patients underwent brain MRI, including conventional sequences, diffusionweighted imaging, susceptibility-weighted imaging, and MR spectroscopy where applicable. Imaging features such as lesion location, signal characteristics, enhancement patterns, diffusion restriction, hemorrhage, necrosis, and perilesional edema were analyzed. Results: Cerebral metastases demonstrated variable MRI appearances depending on the primary tumor. Lung carcinoma metastases commonly showed cystic lesions with ring enhancement and disproportionate perilesional edema. Hemorrhagic metastases were identified on SWI, particularly in metabolically active lesions. Rare metastatic patterns, such as those from salivary gland tumors, showed extensive multifocal involvement. Diagnostic challenges were encountered in differentiating metastases from primary brain tumors and vascular lesions, especially in cases with mixed solidcystic components. Conclusion: MRI provides critical diagnostic information in the evaluation of cerebral metastases. Recognition of characteristic imaging patterns and their correlation with primary malignancies can improve diagnostic accuracy, aid in differentiation from primary brain tumors, and guide appropriate patient management. Sujata Publications 2026-01-18 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf https://ijidms.com/index.php/files/article/view/31 10.62896/ijidms.2.1.01 International Journal of Integrative Dental and Medical Sciences; IJIDMS: Volume 2, Issue 1, January-June 2026; 1-8 3049-4222 eng https://ijidms.com/index.php/files/article/view/31/37 https://creativecommons.org/licenses/by/4.0

oai:ojs.ijidms.com:article/32 2026-02-14T07:59:52Z files:ART

Anterior Diastema Closure Using Frenectomy and Direct Composite Resin Restoration: A Case Report Pradnya Bansode Seema Pathak Madhuri Ambhure Manav Modi Anterior space closure, Composite resin restoration, Indirect putty, Midline diastema Midline diastema (MD) is defined as a space greater than 0.5 mm between the proximal surfaces of fully erupted maxillary or mandibular central incisors, with a higher prevalence in the maxillary arch. It is commonly observed during the mixed dentition phase and is considered a normal developmental finding, often closing spontaneously after the eruption of permanent maxillary canines. Persistence of MD into adulthood is usually associated with specific etiological factors such as tooth-size discrepancies, excessive incisal overlap, abnormal incisor angulation, generalized spacing, and aberrant labial frenum attachment. A high or hypertrophic labial frenum with fibers extending into the interdental papilla plays a significant role in the development and maintenance of MD by exerting continuous tensile forces that interfere with space closure and increase the risk of relapse. Therefore, elimination of this etiological factor through frenectomy is often recommended prior to restorative intervention. Management of MD may involve orthodontic, surgical, restorative, or multidisciplinary approaches based on the underlying cause. Diastemas primarily caused by tooth-size discrepancies are particularly suitable for restorative management. Direct composite resin restorations provide a conservative, cost-effective, and aesthetically predictable treatment option, especially with advances in materials and techniques. This case report highlights the importance of performing frenectomy before direct composite resin closure to achieve stable, functional, and aesthetically pleasing outcomes. Sujata Publications 2026-01-20 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf https://ijidms.com/index.php/files/article/view/32 10.62896/ijidms.2.1.02 International Journal of Integrative Dental and Medical Sciences; IJIDMS: Volume 2, Issue 1, January-June 2026; 09-15 3049-4222 eng https://ijidms.com/index.php/files/article/view/32/38 Copyright (c) 2026 International Journal of Integrative Dental and Medical Sciences https://creativecommons.org/licenses/by-nc/4.0

oai:ojs.ijidms.com:article/33 2026-01-21T15:00:54Z files:ART

Aesthetic Rehabilitation with Direct Composite Veneering using single shade composite resin: A Case Report Pradnya V. Bansode Madhuri Wavdhane Seema Pathak Shweta Chavan Errosion, Minimal Invasive Dentistry, Direct composite Resin Restoration, Single Shade Composite Resin. Tooth wear is defined as the loss of dental hard tissues caused by non-carious factors, including attrition, abrasion, and erosion, and may present as localised or generalised defects. The 2017 European expert consensus recommends delaying indirect restorative procedures and prioritising minimally invasive, additive approaches. Direct composite veneers represent a conservative and effective option for managing tooth wear, particularly in young patients, individuals with healthy dentition, or those with financial limitations. This case report describes a minimally invasive technique for the management of tooth wear associated with dental erosion and caries using single-shade direct composite veneers, demonstrating functional and aesthetic rehabilitation while preserving tooth structure. Sujata Publications 2026-01-21 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf https://ijidms.com/index.php/files/article/view/33 10.62896/ijidms.2.1.03 International Journal of Integrative Dental and Medical Sciences; IJIDMS: Volume 2, Issue 1, January-June 2026; 16-19 3049-4222 eng https://ijidms.com/index.php/files/article/view/33/39 Copyright (c) 2026 International Journal of Integrative Dental and Medical Sciences https://creativecommons.org/licenses/by-nc/4.0

oai:ojs.ijidms.com:article/34 2026-01-21T15:16:24Z files:ART

Single-Shade Universal Composites in Restorative Dentistry: A Review of Omnichroma Pradnya Bansode Sadashiv Gopinath Daokar Shruti Bajaj OMNICHROMA, Tokuyama Dental, Restorative Dentistry The emergence of single-shade universal resin composites marks a paradigm shift in restorative dentistry, simplifying the complex and error-prone process of colour matching. OMNICHROMA (Tokuyama Dental) is the foremost product in this category, employing a sophisticated "Smart Chromatic Technology" based on structural colouration rather than traditional pigment inclusion. This comprehensive review synthesizes recent in vitro and clinical evidence, focusing on OMNICHROMA's unique mechanism, optical performance, clinical efficacy, and physical properties, including surface roughness and repair bond strength. Literature confirms OMNICHROMA’s superior blending effect, leading to excellent visual colour matching across the VITA classical range, often comparable to dedicated multi-shade composites. While instrumental colour measurements sometimes exceed perceptibility thresholds for specific optimal shades, the material's strong chameleon effect ensures high visual acceptability and patient satisfaction, confirming its clinical reliability in both anterior and posterior restorations. Furthermore, OMNICHROMA demonstrates comparable resistance to aging effects and successful repairability when appropriate surface conditioning is utilized, solidifying its position as a reliable, time-saving aesthetic solution. Sujata Publications 2026-01-21 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf https://ijidms.com/index.php/files/article/view/34 10.62896/ijidms.2.1.04 International Journal of Integrative Dental and Medical Sciences; IJIDMS: Volume 2, Issue 1, January-June 2026; 20-23 3049-4222 eng https://ijidms.com/index.php/files/article/view/34/40 Copyright (c) 2026 International Journal of Integrative Dental and Medical Sciences https://creativecommons.org/licenses/by-nc/4.0

oai:ojs.ijidms.com:article/38 2026-02-17T05:26:33Z files:ART

AI-Driven Oral Disease Diagnosis: A Review of the SwaLife Image-Based Model Training and Detection Platform Pravin Badhe Supriyo Acharya Artificial Intelligence; Deep Learning; Convolutional Neural Networks; Oral Disease Diagnosis; Image Classification; SwaLife Platform; Dental Informatics; Early Detection; Machine Learning; Medical Image Analysis. Oral diseases represent a significant global health burden, affecting millions and contributing to substantial morbidity and mortality when diagnosis is delayed. While conventional diagnostic approaches rely on clinical expertise and histopathological confirmation, they remain subject to inter-observer variability, subjectivity, and limited accessibility in resource-constrained settings. The emergence of artificial intelligence (AI) and deep learning technologies offers transformative potential for oral disease detection. This review examines the SwaLife Oral Disease Diagnosis platform, a userfriendly, web-based tool that democratizes AI-driven diagnostics by enabling clinicians, researchers, and educators to train customized machine learning models using their own datasets of healthy and diseased oral images. We describe the platform's architecture, workflow, and capabilities, highlighting its disease-agnostic design, intuitive interface, and capacity for rapid deployment. Through a case study of oral cancer detection, we demonstrate the platform's diagnostic performance and clinical utility. Comparative analysis with existing AI-based oral diagnostic systems reveals SwaLife's unique strengths in user-controlled model training, customizability, and accessibility. We discuss applications ranging from clinical screening and early detection to dental education and telemedicine, while addressing limitations and regulatory considerations. Future directions include integration of 3D imaging, automated lesion segmentation, and federated learning frameworks. The SwaLife platform represents a pragmatic bridge between advanced AI innovation and practical clinical implementation, contributing to the democratization of intelligent oral disease diagnostics in diverse healthcare settings. Sujata Publications 2026-02-14 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf https://ijidms.com/index.php/files/article/view/38 10.62896/ijidms.2.1.05 International Journal of Integrative Dental and Medical Sciences; IJIDMS: Volume 2, Issue 1, January-June 2026; 24-31 3049-4222 eng https://ijidms.com/index.php/files/article/view/38/42 https://creativecommons.org/licenses/by/4.0

oai:ojs.ijidms.com:article/39 2026-04-30T05:51:46Z files:ART

Effect of Kenaf Fiber Reinforcement on the Flexural Strength of Pmma-Based Temporary Crown and Bridge Material: An in-vitro Study Sarang Garg Nachiket Revankar Roseline Meshramkar Lekha Krishnapillai Harikesh Rao kenaf fiber; provisional restorations; polymethyl methacrylate; flexural strength; natural fiber reinforcement; temporary crown and bridge material Purpose: To evaluate the effect of kenaf (Hibiscus cannabinus L.) fiber reinforcement on the flexural strength and yield behavior of polymethyl methacrylate (PMMA)-based temporary crown and bridge material. Materials and Methods: Pretreated kenaf fibers (6 mm length) were incorporated at 2 wt% into a self-cure PMMA provisional material (DPI Self-Cure Tooth Moulding Material, DPI, Mumbai, India). Rectangular specimens (65 × 10 × 3 mm; n = 10 per group) conforming to ADA Specification No. 12 were fabricated for two groups: Group A (unmodified PMMA control) and Group B (kenaf-reinforced PMMA). Three-point flexural testing (span 32.5mm, crosshead speed 2 mm/min) was performed on a universal testing machine. Flexural strength and 0.2% offset yield stress were calculated and compared using an independent t-test (α = 0.05). Results: The kenaf-reinforced group exhibited marginally lower mean flexural strength (70.04 ± 6.60 MPa) compared to the control (71.99 ± 11.06 MPa), with no statistically significant difference (p =0.638). The 0.2% offset yield stress for Group B (59.35 ± 10.83 MPa) was marginally higher than Group A (58.02 ± 5.75 MPa), but this difference was also not statistically significant (p = 0.760). Conclusion: Incorporation of 2 wt% kenaf fibers did not significantly enhance flexural strength or yield resistance of PMMA provisional material. Further investigation with optimized fiber surface treatment, concentration, and orientation is warranted to achieve clinically meaningful mechanical improvements. Sujata Publications 2026-04-29 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf https://ijidms.com/index.php/files/article/view/39 10.62896/ijidms.2.1.06 International Journal of Integrative Dental and Medical Sciences; IJIDMS: Volume 2, Issue 1, January-June 2026; 32-38 3049-4222 eng https://ijidms.com/index.php/files/article/view/39/43 https://creativecommons.org/licenses/by/4.0